{"id":951,"date":"2017-11-03T19:27:00","date_gmt":"2017-11-03T11:27:00","guid":{"rendered":"https:\/\/apcf-infosite-dev.hkust.edu.hk\/?page_id=951"},"modified":"2017-11-03T19:27:00","modified_gmt":"2017-11-03T11:27:00","slug":"sample-size-you-need-to-do-a-power-calculation","status":"publish","type":"page","link":"https:\/\/apcf-infosite.hkust.edu.hk\/?page_id=951","title":{"rendered":"Sample size &#8211; you need to do a power calculation!"},"content":{"rendered":"<p>PG Students must learn that good researchers cannot and will not do research based on convenience or the constraints an animal quotas or limited time opportunities \u2013 Good research is based upon and determined valid statistical analysis, so you <strong>need to conduct<\/strong> a power calculation to estimate your sample size<\/p>\n<p>Work that is not statistically valid is not going to be published and to comply with the 3Rs you must only use animals for research that will produce statistically meaningful result (whether that result proves the null hypothesis or disproves the null hypothesis) otherwise the animals are wasted and that is against the philosophy of the 3Rs<\/p>\n<p><a href=\"http:\/\/www.sample-size.net\/\">http:\/\/www.sample-size.net\/<\/a><\/p>\n<p><a href=\"https:\/\/www.stat.ubc.ca\/~rollin\/stats\/ssize\/n2.html\">https:\/\/www.stat.ubc.ca\/~rollin\/stats\/ssize\/n2.html<\/a><\/p>\n<p><a href=\"http:\/\/www.3rs-reduction.co.uk\/html\/6__power_and_sample_size.html\">http:\/\/www.3rs-reduction.co.uk\/html\/6__power_and_sample_size.html<\/a><\/p>\n<p><a href=\"http:\/\/www.lasec.cuhk.edu.hk\/sample-size-calculation.html\">http:\/\/www.lasec.cuhk.edu.hk\/sample-size-calculation.html<\/a><\/p>\n<p>If you don&#8217;t know the variables for\u00a0 inputting into the calculators, then your literature search should be able to reference the variables for the calculator. If the variables required to plug into the calculator are not able to be found in the literature then a pilot study of N=3 -5 animals is justified to get a mean and SD.<\/p>\n<p><strong>Remember a pilot study needs IACUC approval<\/strong><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>PG Students must learn that good researchers cannot and will not do research based on convenience or the constraints an animal quotas or limited time opportunities \u2013 Good research is based upon and determined valid statistical analysis, so you need to conduct a power calculation to estimate your sample size Work that is not statistically &hellip; <a href=\"https:\/\/apcf-infosite.hkust.edu.hk\/?page_id=951\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Sample size &#8211; you need to do a power calculation!&#8221;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/apcf-infosite.hkust.edu.hk\/index.php?rest_route=\/wp\/v2\/pages\/951"}],"collection":[{"href":"https:\/\/apcf-infosite.hkust.edu.hk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/apcf-infosite.hkust.edu.hk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/apcf-infosite.hkust.edu.hk\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/apcf-infosite.hkust.edu.hk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=951"}],"version-history":[{"count":1,"href":"https:\/\/apcf-infosite.hkust.edu.hk\/index.php?rest_route=\/wp\/v2\/pages\/951\/revisions"}],"predecessor-version":[{"id":952,"href":"https:\/\/apcf-infosite.hkust.edu.hk\/index.php?rest_route=\/wp\/v2\/pages\/951\/revisions\/952"}],"wp:attachment":[{"href":"https:\/\/apcf-infosite.hkust.edu.hk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}